Clarion and Crystal-Clear Cell Acanthoma Reviewed_ Crimson Publishers
Clarion and Crystal-Clear Cell Acanthoma Reviewed by Anubha Bajaj* in Crimson Publishers: Telemedicine and eHealth Journal Clear cell acanthoma or Degos’ acanthoma or pale cell acanthoma is an exceptional, asymptomatic, cutaneous benign tumefaction of obscure etiology, emerging from epidermal keratinocytes. Solitary or multiple dome shaped lesions or well delineated nodules or plaques are frequently cogitated on distal extremities. Typically, clear cell acanthoma exhibits a “stuck on” appearance akin to seborrheic keratosis, “vascular countenance” of pyogenic granuloma, “ scaling and exudation ” elucidated in eczematous reactions and a “progressive margin “associated with an epithelioma. Clear cell acanthoma depicts uniform, pale keratinocytes or pale epithelial cells with abundant cytoplasm composed of excessive glycogen, centric nuclei and distinct foci of transformation. Clinical segregation is required from dermatofibroma, pyogenic granuloma, irritated seborrheic keratosis,...